Notch receptors are clustered and trans-endocytosed by Delta ligand cells. Confocal micrograph of a Delta expressing cell (left) interacting with a Notch expressing cell (right). Following interaction with Delta (blue), cell surface Notch (yellow) is clustered at cell-cell interfaces. Notch extracellular domain is detected within Delta cells (green) indicative of trans-endocytosis. Endocytosis of ligand while bound to Notch may produce a force sufficient to pull Notch apart and activate signaling.
 
 
 
 
 
 

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ASCB

The American Society for Cell Biology (ASCB) was founded in 1960 to bring the varied facets of cell biology together. The Society's purpose is to promote and develop the field of cell biology. Its objectives are achieved through the scholarly dissemination of research at its Annual Meeting and Summer Meetings in its publications. The ASCB strives to ensure the future of basic scientific research by providing training and development opportunities for students and young investigators, and also by keeping Congress and the American public informed on the importance of biomedical research. Since its founding, the ASCB has grown to more than 11,000 members. Members are located throughout the United States and in 50 foreign countries.

Members of ASCB are entitled to a substantial discount when subscribing to Traffic, i.e. $163 for 12 issues (print+online). Please contact the ASCB at ascbinfo@ascb.org.  

 

ELSO - European Life Scientist Organization View the website

This is an exciting time to be a biologist. Cellular machinery is being unravelled at an increasing pace and we are moving from molecules to mechanisms. The barriers between disciplines are disappearing. Biochemists, cell biologists, developmental biologists, geneticists, immunologists, microbiologists, molecular biologists, neurobiologists, and pharmacologists are now all using the same molecular tools and speaking the same scientific language. To catch and hold this excitement, European Life Scientists need a meeting similar to the successful US meetings like the one organized by the American Society for Cell Biology every year.

Therefore a new organization named ELSO - European Life Scientist Organization was launched which will work in parallel with the existing national and international societies. Its initial goal will be to organize meetings in European cities that each year provide a high profile international forum serving the interests of our scientific community. Its defining characteristic will be that it promotes the science and activities of European biologists using molecular tools without regard to national interests. The highlight of the meeting will be the poster sessions which will take place in the midst of the scientific exhibition. The scientific exhibition is planned to become the prime opportunity for the industry to present its products to the European scientific community. A major goal of the meeting is to stimulate and promote mobility and scientific collaboration in Europe. Another important function will be to promote the public understanding of new developments in the life sciences and to provide a critical forum for discussing their implications for society.

 

Elso GazetteThe ELSO Gazette

The official magazine of the European Life Scientist Organization.

The ELSO Gazette is a non-profit electronic magazine owned wholy by the European Life Scientist Organization. Its objectives are to shine a spotlight on the excellent research being carried out by scientists across Europe who work with molecular tools to study all aspects of life, and to report and discuss all aspects of science policy, politics and events relevant to the community it hopes to serve.

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