Volume 8 issue 12 December 2007
Dyneins across eukaryotes: a comparative genomic analysis
Bill Wickstead and Keith Gull

Supplemental Figure 1. Sources and versions of genomic data used in this work.

Figure 1 (.pdf)

Supplemental Figure 2. Unique identifiers and descriptions for the repertoires of DHC, IC and Tctex1/2 sequences encoded in the genomes of 24 diverse eukaryotes.

Figure 2 (.xls)

Supplemental Figure 3. Majority rule consensus trees with bootstrap support for dynein heavy chains, as inferred using Bayesian (partial sequence resampling), Maximum Likelihood, Neighbour-Joining and Maximum Parsimony approaches (see Methods).

Figure 3 (.pdf)

Supplemental Figure 4. Majority rule consensus trees with bootstrap support for dynein intermediate chains, as inferred using Bayesian, Maximum Likelihood, Neighbour-Joining and Maximum Parsimony approaches (see Methods).

Figure 4 (.pdf)

Supplemental Figure 5. Majority rule consensus trees with bootstrap support for Tctex1/2 sequences, as inferred using Bayesian, Maximum Likelihood, Neighbour-Joining and Maximum Parsimony approaches (see Methods).

Figure 5 (.pdf)

Supplemental Figure 6. Classification of the divergent Chlamydomonas dynein 206178. Tree shown is the consensus of 10 Bayesian tree inference runs with character resampling. Topology support from Bayesian, Maximum Likelihood, Neighbour-Joining and Maximum Parsimony approaches is shown next to selected nodes.

Figure 6 (.pdf)

Supplemental Figure 7. Histogram showing the distribution of scores for all sequences encoded 24 diverse eukaryotes queried with a hidden Markov model built from an alignment of dynein intermediate chain sequences.

Figure 7 (.pdf)

Supplemental Figure 8. Reciprocal-best-BLAST hits from 24 diverse eukaryotes queried with sequences identified in Chlamydomonas as outer-arm dynein docking complex components, dynein intermediate chains, proteins involved in intraflagellar transport, dynein light chains, dynein light-intermediate chains and radial spoke proteins, and also components of the human cytoplasmic dynein 1 complex.

Figure 8 (.xls)