Volume 8 issue 5 May 2007
The ternary Rab27a:Myrip:MyosinVIIa complex regulates melanosome motility in the retinal pigment epithelium
VS Lopes, JS Ramalho, DM Owen, MO Karl, O Strauss, CE Futter and MC Seabra

Time-lapse movies showing melanosome dynamics in RPE primary cultured cells. Images were captured every 0.5 seconds, and the movies show one in each two frames, at a frame rate of 7 fps.

Movie 1: Wild-type RPE cell - Video 1 (.mov)

Movie 2: shaker-1 RPE cell - Video 2 (.mov)

Movie 3: ashen RPE cell - Video 3 (.mov)

Movie 4: ashen RPE cell transduced with Ad-GFP Rab27a - Video 4 (.mov)

Movie 5: Wild type RPE cell transduced with Ad shRNA-5 Myrip - Video 5 (.mov)

Movie 6: Wild-type RPE cell treated with nocodazole - Video 6 (.mov)

Movie 7: Wild-type RPE cell treated with cytochalasin D; - Video 7 (.mov)

Movie 8: dilute RPE cell. - Video 8 (.mov)